Profit from FnO trading is considered a non-speculative income. As per the Income Tax Act, short-term capital loss (STCL) can only be adjusted against STCG & LTCG.
Hence, you cannot adjust/set off STCL aginst business income (FnO profit).
Here’s an article for your reference on Set Off and Carry Forward of Losses under Income Tax - Learn by Quicko
Hope this helps.